The patent ductus arterial

in the dog



Having visited the site and some insurgent me about being written therein, I would make the corrections that are necessary so that the information is truthful and not fanciful.

The ductus arteriosus is a small blood vessel (1) which connects the pulmonary artery (which goes from the heart to the lungs) to the descending aorta (which leads to heart the blood which is responsible for oxygen in the lungs) this during life in the womb.

In the early days post-natal care, as in humans, this tiny channel closes spontaneously.

It sometimes happens that this channel is not closed, which, over time, will cause a hypo-oxygenation of the blood, and fatigue with increased heart rate.

It is a congenital disease. This is a minor setback. It is also a rare heart disease that may be in the dog cured by surgery.

This intervention will be to go ligating the small channel that is outside of the heart.

After opening the chest and pericardium, the surgeon will either ligation with a special thread on the ship that will waterproof, or put a metal clip that will aim to crush the ship.

Of course, this surgery is closed heart and not from the heart. Interventions requiring open heart establishment of cardiopulmonary bypass (CPB), a technique that is still in the experimental field of cardiac surgery canine, very rare.

The highlight of the ductus arteriosus is first on auscultation, with a very special heart murmur, which means the stethoscope and is supported by echocardiography, which highlights the "leakage" this small blood vessel.

Called "leakage", not a hole that let out the blood on the outside, but this meeting in the ductus arteriosus, oxygenated blood and blood is not. Mrs. Professor Chetboul was able to calculate the speed at which the blood come out of this tiny ship it was open and his response was six meters / second.

Colleen des Trois Maillets
(Tamerlano dei Comte d'Eau x Umilie des Trois Maillets)

Colleen des Trois Maillets was carrying this disease and was operated at the age of five months by the surgical team specialized works in Paris with the cardiology department of Mrs. Chetboul Professor of the Veterinary School of Maisons Alfort.

Colleen has recovered beautifully from this intervention, the same evening, she ate and had a perfectly normal behavior, even a little "speed" for a young surgery.

Since this is a congenital anomaly, il n’y a aucune contre-indication à la reproduction et aucune persistance du canal artériel n’a été détectée sur la descendance de la chienne.

Warning: some breeds are prédisposthere are no cons-indication to reproduction and no ductus arteriosus was detected in the offspring of the dog.ées and inheritance has been demonstrated in the poodle.

Annual monitoring with ultrasound is needed. The latest, conducted by Mrs. Dr. Claude Muller, former student of Professor cardiologist Chetboul, proved strictly normal. So everything is OK.

Opinions seem divided on making the reproduction of dogs presented a PDA. Cardiologists that I've asked have not issued an interdict.

It can be noted that the surgery heals definitely the bitch who leads a life quite normal. Therefore, we can only congratulate fact give the dog proper care.

 

This article would have appeared as complete, ie, with what follows, I requested. There will be a sequel in the next newsletter. So this additional information.

As it is worse than that fool is stuck to his guns and certainty and with no open mind, and to this rare pathology that I met once (Colleen) and more than 20 years breeding of King Charles I, however, wish to review this case and I spoke to Mrs. Marie Abitbol, a geneticist at the Veterinary School of Maisons Alfort.

I would suggest you read the letters we exchanged:

August 30, 2010 at 13:11, OdetteOudart@aol.com wrote:

Hello Madame

If I speak to you today is because as a geneticist, you will most likely enlighten me.

I am a breeder of KING CHARLES (flat side) for 20 years and I would like to know your opinion on the PDA because I confess to being a little puzzled regarding this disease.

I produced in 2007 a female, Colleen, who presented a PDA.

The veterinarian Claude Muller, who is the cardiologist of my breeding had been accessed after a heart murmur auscultation by my vet. Mrs. Muller was highlighted by a PDA ultrasound.

Directed by it to Maisons Alfort, Mrs. Professor Chetboul had confirmed the diagnosis and the bitch was supported by the surgical team partner Maisons Alfort and operated.

Everything is wonderfully well and I really sympathized with Dr. Carlos Carolina who took my dog in for surgery and care for postoperative echocardiographic controls.

At this time, no doctor that I thought I'd reproduce the bitch put me on hold on the inheritance of this disease can be.

So I reproduce Colleen, 2 times with 2 different males and no puppy presented this pathology.

I must tell you that I work on generations of dogs and, on this line, I had produced the great-grandmother, mother and Collen, and of course laid Colleen.

Grandmother of Colleen, Nicotine, not wearing my kennel but falls straight Jezebel.

No upward Colleen has been affected by the PDA product or puppy reaches PDA, except Umilie healthy on the heart (like all my breeding controlled by Mrs. Muller) which produced Colleen. I enclose the pedigree.

Having a site breeder read in an article that should be removed from breeding dogs that pass (above example will of course, let's not masochistic) and on the same site in another article he had consistently remove the breeding dogs with the PDA, I admit I do some nodes against these tips seem contradictory.

How do I know that transmit reproductive reached or not if it displaces systematically reproduction? All issues that bothers me.

Having spent my entire career in the Paris hospitals and became aware of the benefits of good health, I am very attentive to the various pathologies that can present my little Kings.

In the pedigree that I attach only 2 dogs are unknown to me: Tropic Topaz father side and Noémie, mother side. I can say that all the others were not affected by this disease .

Nevertheless, now the trouble is in my mind.

I do, in your opinion, cease to breed Colleen???

Thank you in advance, Madam, please give me your opinion.

Accept, I pray you, Madam the assurances of my best feelings.

O.OUDART.

Elevage des Trois Maillets
King Charles Spaniels
Odette Oudart
03 21 04 56 74
www.destroismaillets.fr

-----Original Message-----
From: ABITBOL Marie <m.abitbol@vet-alfort.fr>
Subject: Re: Demande de conseils.
Date: Thu, 30 Sep 2010 16:03:57 +0200
To: OdetteOudart@aol.com


Hello,

As promised, here are some answers :

PDA is described in many breeds (especially small breeds) but its determinism remains unclear.

It has been described as a clear hereditary transmission mode complex (polygenic: Several genes involved) in the Poodle (miniature and toy, article of 1971!).

In addition, the study found PDA lesions in dogs with an a priori form non-familial (sporadic cases as your Colleen, it seems) showed that these dogs had lesions similar to those of dogs with familial.

Breeds studied were Colley, the Cocker Spaniel, German Shepherd, the Keeshond, the Pomeranian, Shetland and the Shih Tzu (one dog by breed, item 2003).

The paper concludes with a probable genetic origin of the PDA in these races and recommends excluding all breeding dogs with PDA, regardless of their breed .

Finally, in humans, there are familial and sporadic forms.

In conclusion, given the net predisposition of certain breeds (especially the Cavalier King Charles, a cousin of your race), it is not advisable to breed dogs with (Colleen so) as well as dogs that have produced dogs with (his parents). The descendants of brothers and sisters Colleen, they have reproduced, should be monitored.

I would add that, given the rarity of the anomaly in the tradition of Colleen, the risk of recurrence is small, but should be monitored.

Thank you for your patience .

Sincerely,
Marie Abitbol

Dr. Marie ABITBOL
Consultation de Génétique
UMR955 Génétique Fonctionnelle et Médicale
Ecole Nationale Vétérinaire d'Alfort
7 avenue du Général de Gaulle
94704 Maisons-Alfort Cedex
Tel: 01 43 96 70 01
m.abitbol@vet-alfort.fr

 

As noted by Mrs. Abitbol, if Colleen is sporadic (isolated) and knowing the four previous generations with whom I produced: Funny Girl des Rois de l'Eure, Jezebel des Trois Maillets, Nicotine de Sorine, Umilie des Trois Maillets, mother of Colleen, I have never had a single case of PDA, or any other heart problem.

Not having been more caution by veterinarians, which I said that I will reproduce Colleen, a probable genetic transmission of this anomaly, I do not feel at all guilty of married Colleen. Both progenies showed no heart problems.

In this case, all breeders working with descendants of this line, known (from Funny Girl) to be free, have this sword of Damocles hanging over their heads, ready to fall upon them in their lower production!!!!!!!!!!!!!!!!!!!!!

Stop playing psychodrama!!!!!!!

Mrs. Abitbol have informed our lantern and with this obligation, which must always be present to our mind: be careful, whatever the pathology, and do according to his conscience and the results of scientific studies, if any, but he must also know how to decipher the past for special cases.







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